Reviewed by Alex SmithFeb 7 2022
The kidneys are essential organs that purify the blood and influence a number of bodily functions. Numerous kidney diseases, at first, exhibit neither symptoms nor pain.
Humboldt Research Fellow Dr. Maria Rita Ortega Vega from the Universidade Federal do Rio Grande do Sul in Brazil will be a guest at the Faculty of Chemistry and Food Chemistry at TU Dresden. Here, she will work together with her host Prof. Stefan Kaskel on the development of novel electrochemical sensors for the salivary detection of kidney diseases. Image Credit: TU Dresden
In most cases, it is only as an outcome of a chance examination that proteins or only microscopically visible traces of blood in the urine specify kidney damage.
The Brazilian material scientist Dr. Maria Rita Ortega Vega is keen to develop a totally new technique for the early detection of kidney disease at the Technische Universität Dresden.
She is working together with host Prof. Stefan Kaskel and his team as part of a Humboldt research stay. Kaskel is a professor of inorganic chemistry and is mainly involved in the study of porous materials, e.g., for environmental technologies or for the energy transition.
However, Dr. Ortega Vega desires to make use of these materials in her project "Nanostructured transition metal-based electrochemical sensor for salivary urea detection for kidney failure diagnostics" to detect and measure urea in saliva using electrochemical methods.
The presence and amount of urea in saliva can be an indicator of kidney problems. With such a sensor, patients and doctors can get reliable results quickly and without blood testing. For patients who are already in the chronic stage of the disease, this technology can help evaluate the performance of the dialysis process. We expect to jointly develop a specific and sensitive material for this application.
Dr Maria Rita Ortega Vega, Humboldt Research Fellow, Department of Inorganic Chemistry, Technische Universität Dresden
"I am delighted that we have been able to attract Ms. Ortega, a talented young scientist who is an excellent fit for our team, to TU Dresden. Her innovative research into new topics in biosensorics will certainly benefit decisively from the excellent research environment in Dresden," states Prof. Kaskel.
As a Henriette Heart Scout of the Alexander von Humboldt Foundation, he has the chance to ascertain three outstanding and greatly sought-after young scientists from abroad, to recommend them for a Humboldt Research Fellowship, and to invite them to the TU Dresden. Maria Rita Ortega Vega is the first fellow Kaskel selected for his team in this manner.
I liked the level of work of the team: there are many promising developments here with great opportunities for technology transfer and applicability. This is very important to me: doing science that can have an impact on society. I consider science as a democratic project, so studying systems and materials that are scalable to make them reach people by means of different applications and that can make life easier, “materializing” knowledge, is a huge motivation.
Dr Maria Rita Ortega Vega, Humboldt Research Fellow, Department of Inorganic Chemistry, Technische Universität Dresden
“I also liked the infrastructure, which is very different from the one in Brazil. TUD has different technologies and equipment that I am not used to and I'm looking forward to learning about them," Maria Rita describes her motivation to accept the invitation Stefan Kaskel extended to her to come to Dresden.