Dissolved carbon dioxide sensors are in-line sensors that continuously monitor dissolved CO2 levels in biopharmaceutical and brewing processes.
For bioprocessing, dissolved CO2 probes allow in situ CO2 monitoring in bioreactors to manage production, assure appropriate scaling up, and maximize yield. In brewing, a dissolved CO2 sensor can check important quality parameters and maintain consistent mouthfeel.
CO2 InPro Sensors
The on-line InPro CO2 probes (models InPro5000i/12/120, InPro5000i/12/220, and InPro5000i/12/320) are sensors with ISM that enable precise measurement and control of dissolved CO2 in biopharmaceutical applications. They are based on the well-known Severinghaus approach to CO2 measurement.

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- Measurement Parameter: Carbon Dioxide
- Measurement Technology: Potentiometric Severinghaus
- Measurement Range (Concentration): 0.145-14.5 psig pCO2
- Primary Media/Application: Pharmaceutical/Life Science Production
CO2 Sensor InPro5500i/Var. Type N

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The InPro 5500i Varivent is a thermal conductivity CO2 sensor ideal for tracking carbonation levels for quality control of beer and soft drinks. Its ISM technology lowers sensor lifetime costs and streamlines handling.
- Measurement Parameter: Carbon Dioxide
- Measurement Technology: Thermal Conductivity
- Measurement Range (Concentration): 0…145 psig pCO2
- Primary Media/Application: Food and Beverage
Reliable CO2 Sensors for Improved Cell Culture Processes
In line Control of CO2 for Improved Cell Culture Processes
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This video illustrates how CO2 sensors offer the continuous, real-time data required to enable an effective control strategy in mammalian cell culture processes, improving process yield and the quality of the end product.
Real-time Monitoring for Immediate Feedback

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In situ CO₂ sensors deliver real-time, precise measurements of CO₂ accumulation, enabling rapid response to fluctuations in dissolved CO₂ levels.
Fast Installation and Replacement Capabilities

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Plug and Measure dissolved CO2 sensors provide quick, error-free commissioning and installation. These CO2 sensors have few replacement parts to reduce maintenance effort.
CO2 Sensors with a Hygienic Design for Food & Pharma

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The FDA-compliant materials used in constructing METTLER TOLEDO dissolved CO2 sensors guarantee that all CO2 probes are completely sterilizable in situ or in an autoclave and can survive CIP procedures.
Simplify Maintenance with ISM Diagnostics

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Intelligent Sensor Management (ISM)-enabled CO2 sensors offer sophisticated diagnostics to increase sensor dependability. ISM guarantees that maintenance is only carried out when necessary and helps prevent sensor failure.
Increase Cell Growth Rates in Biotech Applications

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Unwanted metabolic changes and decreased productivity are caused by high dCO2 levels. Rapid response to CO2 changes made possible by a dissolved CO2 sensor can boost cell growth rates by up to 30%.
Fast Membrane Replacement for Breweries

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Brewery CO2 sensors from METTLER TOLEDO only need two parts to replace the membrane, which speeds up the process and can be completed in 30 seconds.
CO2 Probes Help Meet Regulatory Requirements

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These CO2 sensors provide predictive sensor health diagnostics, track calibration records, and count the exposed number of autoclave cycles to assist in meeting regulatory compliance requirements.